Bioinformatics and AVATAR
Avandia is an oral medication used to treat Type II diabetes. It is manufactured by GlaxoSmithKline and was approved by the FDA. So far the diabetes drug has been used by over 6 million people worldwide, and could be responsible for thousands of heart attacks and deaths every year.
Tumor suppressor genes by definition are genes that are coding for proteins acting as a break on cancer. This group of genes function as a break mechanism when cells accelerate towards cancer. In basic terminology, the role of tumor suppressors is to stop cancer cells. P53 is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is important in multicellular organisms, where it regulates the cell cycle and thus directly functions as a tumor suppressor by stopping cell cycle or by killing the cancer cells by apotheosis.
Pharma, biotech and agriculture markets as well as academic institutions are craving for DNA sequence information as their future is depending on genome data in silico. Scientists understand the business side of the sector, and realize that outsourcing can be a pretty cost efficient way to get the data they need, rather than investing in the resources to perform the sequencing in their labs. In addition, outsourcing gives these institutions the ability to focus their efforts on their core competencies, usually drug discovery and development, instead of acquiring the tools for sequencing.
Is there something like American Genes, a group of genes that is unique to USA ?
The following NY-times article is the answer.
http://www.nytimes.com/2010/02...
Relevant:
http://www.theroot.com/
http://www.cyberpursuits.com/g...
http://AfricanDNA.com
The Genome Reviews database provides an up-to-date, standardized and comprehensively annotated view of the genomic sequence of organisms with completely deciphered genomes. Currently, Genome Reviews contains the genomes of archaea, bacteria, bacteriophages and selected eukaryota. Genome Reviews is available as a MySQL relational database, or a flat file format derived from that in the EMBL Nucleotide Sequence Database.
MySQL is a convenient platform for open source data transactions. That means genetic data of nearly all available species can be uploaded and retrieved.
Jan. 21, 2010: Toyota recalls 2.3 million Toyota vehicles in a U.S. since a accelerator pedal can stick, causing unintended acceleration. It is not associated to a building pad recall, nonetheless about 1.7 million of a vehicles have been additionally concerned in both recalls. Models concerned have been a 2009-2010 RAV4, 2009-2010 Corolla, 2009-2010 Matrix, 2005-2010 Avalon, sure 2007-2010 Camrys, 2010 Highlander, 2007-2010 Tundra, 2008-2010 Sequoia.
Jan. 26: Toyota at a moment suspends U.S. sales of a 8 models whose accelerator pedals can stick.
Amyloid beta (Aβ or Abeta) is a peptide of 39–43 amino acids that appear to be the main constituent of amyloid plaques in the brains of Alzheimer's disease patients.
The protein fragment, Aβ, that is broken down in a normal brain, begins to accumulate into tiny clusters known as plaques. These plaques exist between nerve cells in the brain and have the effect of destroying nerve tissue. It has been known for some time that the higher the levels of beta amyloid in the brain the greater the level of brain impairment.
In December 2009 the US Senate passed a $636 billion annual budget for defense 88-10 and immediately went back to arguing about spending less than $100 billion a year to see that all Americans get the health care they need.
My grand mother used to say "do not compare apples with oranges" but the spending on apples and the spending on oranges are good indications of their relative worth.
I am wondering about the number of people employed by the military industry and the number of people employed by the health care industry.
Anybody knows that ?
Genetics is a abstract concept. Everybody knows that genetics is about DNA, about genes, diseases and about your children. But the details are obscure to the general public. How genes are associated with diseases ? How a disease is transmitted from your grand parents to your children ? These are important questions.
However, if you try to explain these with scary terminology such as epigenetics, neural pathways, biotechnology, dominant inheritance, gene-methylation you more often scare the average Joe.
Do you remember the modeled characters in AVATAR ? The movie was not science-fiction shoot in a cheap studio. The characters were actual living chracters in silico, in the computer. Human or MA-VI characters were modeled and computers calculated every single move in real-time. This is the digital technology of today.
Imagine, with the ever growing computational power, every single DNA base of your genetic material and every single amino-acid of your flesh and bone is modeled and computers calculate every move of your genes, your muscles, your sperms.
